2'-F-dU Phosphoramidite

2'-F-dU Phosphoramidite
CAS NO. 146954-75-8

5'-O-DMT-2'-Fluoro-2'-deoxyuridine 3'-CE phosphoramidite

The 2'-F-dU Phosphoramidite is a chemical compound with the CAS number 146954-75-8. It is a modified nucleotide that contains a fluorine atom in the 2' position of the deoxyuridine sugar. This modification enhances the stability of RNA and DNA molecules by increasing their resistance to enzymatic degradation, making it useful in various biological and medical applications. The phosphoramidite form of the nucleotide allows for the efficient and specific incorporation of 2'-F-dU into oligonucleotide sequences during chemical synthesis.

Features of 2'-F-dU Phosphoramidite

2'-F-dU Phosphoramidite is a dependable and top-quality choice for oligonucleotide synthesis, categorized as a 2'-F phosphoramidite and assigned a synonym of DMT-2'-F-dU Phosphoramidite, along with a CAS number of 146954-75-8. This alteration enhances stability and fortifies the resistance against nuclease activity, suitable for nucleic acid-based applications. Its creation follows rigid quality standards for purity and minimal impurities, and the product is packaged for hassle-free use in oligonucleotide synthesis. This phosphoramidite is versatile and can be utilized in various nucleic acid technologies, including CRISPR-Cas9 gRNA.

Technical Data of 2'-F-dU Phosphoramidite

Product CodeCAS NO.ProductMolecular FormulaMolecular WeightPurityAppearanceStorage Conditionswater
HR-00204005146954-75-82'-F-dU PhosphoramiditeC39H46FN4O8P748.789≥99%White to Off-white powder-20℃≤0.3%

nucleoside nucleotide and nucleic acid
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